Pat O'Connell wrote:

Background: among other things I'm a chemist

I am too.

High temnperature testing cannot simulate some failure mechanisms.

And example might be surface cracking of photo paper (a terrible
problem with the first generation of Kodak resin coated paper.)
What happens is that the stress that causes the cracking is annealed
out at modestly high temperatures. The underlying cause of the stress
may be speeded up, but the annealing out is speeded up more.

Doug McDonald